Polymers have been emerging to be the cornerstones for therapeutic applications as well as the largest and versatile class of biomaterials. Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Synthetic poly (lactic-co-glycolic acid) (PLGA) is widely considered as a base material for biomedical applications due to its good biocompatibility and degradability. The use of synthetic poly (amino acids) as polymers for biomedical devices would seem a logical choice, given their wide occurrence in nature. In summary, this special issue connects the synthetic polymers to biomaterials science and engineering. Peer review under responsibility of Southwest Jiaotong University. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Research pertaining to conductive polymers has gained significant traction in recent years, and their applications range from optoelectronics to material science. This review gives a brief overview about the introduction and developments of polymers in medicine in general, addressing first stable polymers, then polymers with degradability as a first biological function, followed by various other functional and responsive polymers. Multiple biological, synthetic and hybrid polymers are used for multiple medical applications. In the article “Influence of Processing Conditions on the Mechanical Behavior and Morphology of Injection Molded Poly(lactic-co-glycolic acid) 85:15,” an overview is provided among processing conditions, morphology, and mechanical property relationship of injection molded PLGA. The very first reported synthetic polymer for medical use is poly (methyl methacrylate) (PMMA) by a British ophthalmologist, Sir Nicholas Harold, in 1949 for making intraocular lens [2]. The book opens by presenting important background information on polymer chemistry and physicochemical characterization of polymers. Hydrogels are three-dimensional hydrophilic polymeric networks that can be made from a wide range of natural and synthetic polymers. For Authors For Reviewers For Editors For Librarians For Publishers For Societies. New York, USA – December 24, 2020 – In December 2020, the US-based chemical supplier, Alfa Chemistry announced the launch of a new sub-website for the supply of functional polymers, including Adsorptive Polymers, Biomedical Polymers, Electrofunctional Polymers, Functional PEGs, Photoactive Polymers, Silicone Polymers and more.With unstopping efforts, the company continues to … Therefore, we launch this special issue, including two review articles and four research articles, to summarize the application of synthetic polymers in biomedical engineering and to illustrate the new development of polymeric biomaterials. Biomedical Applications of Synthetic and Natural Biodegradable Polymers Manpreet Kaur Department of Biotechnology, Himachal Pradesh University, Summerhill, Shimla, India Synthetic polymers responsive to temperature and/or pH changes The most studied synthetic responsive polymer is Biomedical applications of composite resorbable fibers 6. ISBN 9780128163498, 9780128166048 This review discusses recent advanced engineering methods to fabricate hydrogels for biomedical applications with emphasis in cardiac constructs and wound healing. However, their application is limited because of their insolubility or pH-dependent solubility and lack of functional groups . Multiple biological, synthetic and hybrid polymers are used for multiple medical applications. Therefore, they are of increasing interest in a wide range of biomedical applications as diverse as tissue engineering, drug delivery, therapeutics, diagnostics, and so on. Review articles are excluded from this waiver policy. Abstract. As a result, a wide range of natural or synthetic polymers able to undergo hydrolytic or enzymatic degradation is being studied for biomedical applications. Resorbable polymers in bone repair and regeneration 5. In practice, however, pure insoluble poly (amino acids) have found little utility because of their high crystallinity, which makes them difficult to process and results in relatively slow degradation. When thinking about biomedical applications beyond mere drugs, e.g. Not to be confused with bioplastics, usually semi-synthetic polymers produced from renewable biomass sources. Biostability and biodegradability are the two important parameters to be noticed to select a … Other polymers used for biomedical applications due to their biocompatibility, controllable degradation rate and their degradation into non-toxic components, include natural polymers, such as polysaccharides or proteins and synthetic polymers, such as: poly(glycolic acid) (PGA), poly(hydroxyl butyrate) (PHB) and poly (ε-caprolactone) (PCL). Natural polymers, or polymers, derived from living creatures, are of great interest in the biomaterials field. Copyright © 2018 Qiang Wei et al. Degradation is important in biomedicine for many reasons. A wide range of different polymers are available, and they have the advantage to be tunable in physical, chemical and biological properties and in a wide range to match the requirements of specific applications. Polymers represent the largest and most promising class of biomaterials. fabricated 3D porous scaffolds via PLGA and another biodegradable synthetic polymer polycaprolactone (PCL) in the article “Application of Synthetic Polymeric Scaffolds in Breast Cancer 3D Tissue Cultures and Animal Tumor Models.” It has proven that cancer cells grown on 3D polymeric scaffolds exhibit distinct survival, morphology, and proliferation compared to those on 2D polymeric surfaces. Synthetic polymers can be designed and synthesized with a broad variety of structures and appropriate physical and chemical properties for suitable applications. Epub 2015 Apr 30. One review article “Strain and Vibration in Mesenchymal Stem Cells” focuses on the effect of various culture conditions and strain or vibration parameters to review the response of mesenchymal stem cells to vibration and cyclic tension and then discuss how polymer scaffolds influence cell response to vibration and strain. Applications of synthetic polymers in clinical medicine. Journals. By continuing you agree to the use of cookies. There is subsequently an overview of the most frequently used polymer classes. Polymers are traditionally used in plastics, rubber, and coatings. 2015 Jun 24;4(9):1386-98. doi: 10.1002/adhm.201500156. It is shown up that biomedical polymers comprise not only bulk materials, but also coatings and pharmaceutical nano-carriers for drugs. This serves as essential scientific support for the subsequent chapters, each of which is devoted to the applications of polymers in a particular medical … Synthetic Polymers for Biomedical Applications, Max Planck Institute for Medical Research, Heidelberg, Germany, University of Freiburg, Freiburg, Germany. Many opportunities exist for the application of synthetic biodegradable polymers in the biomedical area particularly in the fields of tissue engineering and controlled drug delivery. Based on the study of mechanics, PLGA is further processed by injection molding as craniofacial bioresorbable medical devices in the article “Effect of Injection Molding Melt Temperatures on PLGA Craniofacial Plate Properties during In Vitro Degradation.” The mechanical and physicochemical properties of the PGA plates are evaluated in detail during in vitro degradation. A Processable Shape Memory Polymer System for Biomedical Applications Adv Healthc Mater. ... 39 Biomedical polymers are essentially a biomaterial, that is used and adapted for a medical application. Sign up here as a reviewer to help fast-track new submissions. Biopolymers consist of monomeric units that … Biocompatible polymers are both synthetic (man-made) and natural and aid in the close vicinity of a living system or work in intimacy with living cells. These fibers could be formed into different configurations such as single, core–sheath, hollow, blended, or composite according to human needs. The main body of the review then is structured according to the medical applications, where key requirements of the applications and the currently used polymer solutions are indicated. This is attested by their widespread use in various medical applications. Synthetic polymers can be designed and synthesized with a broad variety of structures and appropriate physical and chemical properties, which are of increasing interest in a wide range of biomedical applications as diverse as tissue engineering, drug delivery, therapeutics, diagnostics, and so on. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. In December 2020, Alfa Chemistry announced the launch of a new sub-website for the supply of functional polymers, including Adsorptive Polymers, Biomedical Polymers, Electrofunctional Polymers, Functional PEGs, Photoactive Polymers, Silicone Polymers and more. 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